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Continuous and comparative studies of the plasma-levels of glutamic-oxaloacetic transaminase (G.O.T.), glutamic-pyruvic transaminase (G.P.T.), and ornithine-carbamyl transferase (O.C.T.), as well as the concentration of bromsulphalein (B.S.P.) showed that in experimentally produced hepatitis contagiosa canis (H.c.c.) the plasma-activity of these enzymes and B.S.P. retention were raised and the increased B.S.P. retention correlated in time with the rises in plasmaenzyme activity. A marked leucopenia developed simultaneously with temperature elevations. The lymphocyte/neutrophil ratio changed towards an increase in lymphocytes during the disease. Electrophoretic studies of serum-proteins showed a rise of γ-globulins and a corresponding decrease of the albumins, that is, an unchanged level of total protein. |
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