2,4-Dinitrobenzenesulfonamides: A simple and practical method for the preparation of a variety of secondary amines and diamines

Autor:	Yuko Hidai, Chung-Kuang Jow, Toshiyuki Kan, Mui Cheung, Tohru Fukuyama
Rok vydání:	1997
Předmět:	Primary (chemistry) Chemistry Organic Chemistry Drug Discovery Combined use medicine Organic chemistry Mitsunobu reaction Alkylation Biochemistry Chloride Combinatorial chemistry medicine.drug
Zdroj:	Tetrahedron Letters. 38:5831-5834
ISSN:	0040-4039
DOI:	10.1016/s0040-4039(97)01334-8
Popis:	2,4-Dinitrobenzenesulfonamides, readily prepared from primary amines and 2,4-dinitrobenzenesulfonyl chloride, can be alkylated by the Mitsunobu reaction or by the conventional methods to give N , N -disubstituted sulfonamides in excellent yields. Since 2,4-dinitrobenzenesulfonamides can be removed without deprotecting 2-nitrobenzenesulfonamides, a wide variety of diamines could be prepared by the combined use of these protecting/activating groups.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::76339cb294a52eb42cdd4817f6639d2f https://doi.org/10.1016/s0040-4039(97)01334-8 Zobrazit plný text záznamu Full Text from ScienceDirect