Recent Advances in the Total Synthesis of Steroids

Autor: J. Valls, Gerard Nomine, Leon Velluz
Rok vydání: 1965
Předmět:
Zdroj: Angewandte Chemie International Edition in English. 4:181-200
ISSN: 1521-3773
0570-0833
DOI: 10.1002/anie.196501811
Popis: In the total synthesis of steroids on the industrial scale, three factors are important: stereoselectivity of the reactions used, resolution of racemic intermediates at the earliest possible stage, and convergence of the synthesis. Theoretical advances and wider practical experience in the chemistry of polycyclic compounds have recently led to the development of the first syntheses which are suitable for the industrial production of steroid hormones.
Databáze: OpenAIRE