High bandwidth force estimation for optical tweezers

Autor: Murti V. Salapaka, Tanuj Aggarwal, Hullas Sehgal
Rok vydání: 2009
Předmět:
Zdroj: Applied Physics Letters. 94:153114
ISSN: 1077-3118
0003-6951
DOI: 10.1063/1.3116621
Popis: A prevalent mode of optical tweezers involves position clamping that regulates a constant position of a trapped bead. Traditional schemes employ the measured bead position in the open loop or the control signal in the position-clamp mode as an estimate of external force on the trapped bead. This article shows that traditional methods introduce fundamental limitations on bandwidth of the external force estimation. A method is presented that leads to an order of magnitude increase in the bandwidth of the external force estimation. Furthermore, a comprehensive modeling paradigm is introduced that facilitates estimation of forces on the bead.
Databáze: OpenAIRE