Total Synthesis of Fused Polycyclic Alkaloids Based on Oxidative Phenolic Couplings and Aza-Michael Reactions

Autor:	Kazuo Nagasawa, Minami Odagi
Rok vydání:	2023
Předmět:	Organic Chemistry
Zdroj:	Synlett. 34:1087-1097
ISSN:	1437-2096 0936-5214
DOI:	10.1055/a-2007-9342
Popis:	Alkaloids with fused polycyclic frameworks are attractive targets for synthetic organic chemists because of their structural complexity and biological activities, and a variety of strategies for their synthesis have been developed. Herein, we describe our strategy of utilizing oxidative phenolic coupling and a regioselective intramolecular aza-Michael reaction to generate fused polycyclic structural frameworks, and its application for the total syntheses of (+)-gracilamine and various hasubanan alkaloids.1 Introduction2 Total Synthesis of (+)-Gracilamine3 Synthetic Studies on Monoterpene Indole Alkaloids4 Total Synthesis of Hasubanan Alkaloids5 Summary
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::75e94052386384b27ffcfe2da877d6c2 https://doi.org/10.1055/a-2007-9342 Zobrazit plný text záznamu