| Autor: | Maria Cristina Tanzi, Paola Petrini, Neil B. Graham, C. R. Moran |
|---|---|
| Rok vydání: | 1999 |
| Předmět: |
chemistry.chemical_classification
Materials science Ethylene oxide Maleic acid Bulk polymerization Diol technology industry and agriculture Biomedical Engineering Biophysics Oxide Bioengineering macromolecular substances Biomaterials chemistry.chemical_compound Dicarboxylic acid chemistry Self-healing hydrogels Polymer chemistry Polyurethane |
| Zdroj: | Journal of Materials Science: Materials in Medicine. 10:635-639 |
| ISSN: | 0957-4530 |
| DOI: | 10.1023/a:1008939808819 |
| Popis: | Over the last 30 years, water-swellable and water-insoluble hydrogels have been extensively investigated and developed, leading to a large family of materials which have found uses in a wide range of biomedical applications. While hydrogels usually present a crosslinked structure, linear polyurethane-ureas (PUUs) based on poly(ethylene oxide) have been shown to be able to absorb and swell with aqueous media without dissolving. This behavior is due to the phase separated domain morphology, where hydrogen bonded urethane/urea hard segment domains are dispersed in a PEO soft segment domain. This work investigates the possibility of obtaining linear poly(ethylene oxide)-based polyurethane-amide (PUA) hydrogels using two amide diols as chain extenders, a mono amide diol (AD) and a diamide diol (DD), and a dicarboxylic acid (maleic acid, MA). Poly(ethylene oxide) based PUAs were obtained using a “one-shot” bulk polymerization technique. The chemicophysical characterization and water-solubility tests showed that these materials, while having molecular weights similar to the PUUs, do not possess sufficient phase separation, hydrogen bonding and hydrophobicity of the hard segment domains to exhibit hydrogel behavior. Crosslinked PUAs using maleic acid as chain extender show interesting hydrogel properties. © 1999 Kluwer Academic Publishers |
| Databáze: | OpenAIRE |
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