Effect of Different Solvents on Biginelli Reaction Using Layered Double Hyroxide (LDH) As an Ecofriendly Catalyst

Autor: D. A. Pund, N. S. Ghotkar, B. N. Berad
Rok vydání: 2021
Předmět:
Zdroj: International Journal of Scientific Research in Science and Technology. :223-226
ISSN: 2395-602X
2395-6011
DOI: 10.32628/ijsrst218128
Popis: A simple and efficient method of the 3,4- dihydropyrimidin-2(1H)-ones/thiones synthesis in good to high yield is described. It consists in a one-pot three-component Biginelli condensation using Layered double hydroxide (LDH) as catalyst. The effect of different solvents on the yields of final product also been studied. Highly polar solvent as well as highly non-polar gives less yields in presence of LDH catalyst.
Databáze: OpenAIRE