A model for the implementation of symmetry breaking from B-to-Z-DNA configurations

Autor: M. Reséndiz-Antonio, J. J. Godina-Nava, Agustín Conde-Gallardo, Eloy Ayón-Beato, Juan José Godina-Nava, Martín Hernández-Contreras, Liliana Velasco-Sevilla
Rok vydání: 2012
Předmět:
Zdroj: AIP Conference Proceedings.
ISSN: 0094-243X
DOI: 10.1063/1.3678617
Popis: Supported in the helicoidal model performed by M. Barbi et al, we propose a extended Morse potential version to study the symmetry breaking in a simple non-linear DNA model based in two plane base rotors. The intention is study the development of the intermediate states appearing in the junction B-to-Z DNA, useful for understanding its biological function, once is characterized the phase transition involved. With this model, we make a comparison between the non-linear dynamics of a handedness homogeneous base-pair winding in a right-handed sense and a left handed sense. Numerical results determine that the right-handed sense is the preferential direction of winding of our spring's model that can emulate the common DNA behavior.
Databáze: OpenAIRE