Reaction of nucleobases with α-acetylenic esters, potentially useful for chemical modification of nucleic acids

Autor:	Guy Evrard, F. Durant, J. Y. Le Gall, S. Colinart, Bernadette Norberg, Martin Olomucki
Rok vydání:	1984
Předmět:	Chemistry Stereochemistry Organic Chemistry Chemical modification Cytidine Triple bond Ribonucleoside Biochemistry Nucleobase chemistry.chemical_compound Drug Discovery Nucleic acid Lactam Molecule
Zdroj:	Tetrahedron Letters. 25:3471-3474
ISSN:	0040-4039
DOI:	10.1016/s0040-4039(01)91050-0
Popis:	The NH2 group and the adjacent ring nitrogen of adenosine and cytidine react with α-acetylenic esters by addition across the triple bond and formation of a lactam with the ester group.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::75cf531b6dac19525785250ae92866d4 https://doi.org/10.1016/s0040-4039(01)91050-0 Zobrazit plný text záznamu