A 14-Membered Macrolide and Isocoumarin Derivatives from the Cultured Lichen Mycobionts of Graphis vestitoides

Autor:	Hiromi Miyawaki, Duy Hoang Le, Takao Tanahashi, Nobuo Hamada, Yukiko Takenaka
Rok vydání:	2013
Předmět:	Isocoumarin chemistry.chemical_compound Crustose lichen Chemistry Drug Discovery Botany Graphis vestitoides General Chemistry General Medicine Lichen Isolation (microbiology)
Zdroj:	Chemical and Pharmaceutical Bulletin. 61:358-362
ISSN:	1347-5223 0009-2363
DOI:	10.1248/cpb.c12-00853
Popis:	Spore-derived mycobionts of the crustose lichen Graphis vestitoides collected in Vietnam were cultivated on a malt-yeast extract medium supplemented with 10% sucrose. The investigation of their metabolites resulted in isolation of a novel 14-membered macrolide and a new isocoumarin, together with five known isocoumarin derivatives. Their structures were determined by spectroscopic and chemical means. This is the first instance of isolation of a 14-membered macrolide from a lichen mycobiont.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::75ceab2456e5ebfc300b236190a5fc8a https://doi.org/10.1248/cpb.c12-00853 Zobrazit plný text záznamu