Bio-templated synthesis of mesoporous bioactive glass with a hierarchical pore structure
| Autor: | Xiaodi Niu, Hongsu Wang, Xuliang Deng, Cancan Sun, Xiaohan Gao, Yanan Wang, Jinglong Tang |
|---|---|
| Rok vydání: | 2012 |
| Předmět: |
Materials science
biology Mechanical Engineering Bone implant Condensed Matter Physics biology.organism_classification law.invention Sponge Chemical engineering Mechanics of Materials law Bioactive glass Drug delivery General Materials Science Composite material Mesoporous material Hydroxycarbonate apatite Porous medium Porosity |
| Zdroj: | Materials Letters. 76:237-239 |
| ISSN: | 0167-577X |
| Popis: | The bimodal porous structured mesporous bioactive glass (MBG) materials consisting of macropores were prepared using the natural Mediterranean sea sponge as macropored hard templates and P123 as mesopore soft templates, respectively. The macroporous structures of the natural Mediterranean sea sponge as macropored were replicated with the walls containing highly ordered MBG as well. Dexamethasone (DEX) was employed as a model drug and the release profiles showed that the dual porous materials had a sustained drug delivery capability. In addition, the materials had higher ability to induce hydroxycarbonate apatite (HAp) formation. Therefore, such highly ordered dual pore MBG materials might be used as a bioactive drug release system for preparation of bone implant materials. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect