Autor: |
Otto Hagenbüchle, Ueli Schibler, P. K. Wellauer, H. C. Hurst, Shaw Ph, D. L. Cribbs |
Rok vydání: |
1986 |
Předmět: |
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Zdroj: |
Coordinated Regulation of Gene Expression ISBN: 9781461293156 |
DOI: |
10.1007/978-1-4613-2245-0_7 |
Popis: |
The aim of our studies is to elucidate in molecular detail the principles underlying the tissue specific expression of eucaryotic genes. It is hoped that by understanding how a particular gene becomes activated in one (or a few), but not other tissues we may gain more insight into the complex processes that govern cellular differentiation. The alpha-amylase multigene family of mouse has proven a suitable model system to study tissue specific modulation of gene expression since members of this gene family are expressed with different efficiencies in the pancreas, parotid gland & liver. |
Databáze: |
OpenAIRE |
Externí odkaz: |
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