Autor: |
Siddharth Singh, Satish S.C. Rao, Deborah Dickinson |
Rok vydání: |
2010 |
Předmět: |
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Zdroj: |
Gastroenterology. 138:S-225 |
ISSN: |
0016-5085 |
DOI: |
10.1016/s0016-5085(10)61021-9 |
Popis: |
It is well known that patients with IBS have a high rate of co-morbid extra-intestinal symptoms.Traditional Chinese Medicine (TCM) views all illnesses as arising from global patterns of dysregulation and TCM predicts that despite similar symptoms, subgroups of IBS patients vary in important characteristics such as pain sensitivity and stress responses and these differences reflect different IBS pathophysiology and require different treatment. AIMS: To determine stress reactivity and pain sensitivity of IBS subgroups classified into TCM categories of Excess (Liver Qi stagnation), Deficiency (Spleen Qi deficiency) andOverlap (mixed symptoms). METHODS: 63 ROME III+ female IBS patients (Mean age= 36.38; SD +/13.0) were independently evaluated by two TCM practitioners and also filled out a TCM symptom questionnaire. Sensitivity to pressure pain at three body sites and autonomic responses to a psychological stressor were evaluated in a laboratory session. RESULTS: TCM practitioners agreed on 82.6% of diagnoses (excess=29, overlap=23, discrepancy=11 (not included in further analysis)) although there were not differences in IBS symptom severity by TCM subgroup. Older Excess subjects showed significantly less sensitivity to pressure pain compared to those with overlap (emeans: Excess =9.97+SE 1.08; Overlap = 10.33+ SE 1.06., p |
Databáze: |
OpenAIRE |
Externí odkaz: |
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