Enantiomeric resolution ofN-alkyl-N-methylanilineN-oxides by high-performance liquid chromatography

Autor:	L. A. Damani, Andrew J. Hutt, Mark R. Hadley, J. Murphy, Patrick Camilleri, Harriet G. Oldham
Rok vydání:	1993
Předmět:	chemistry.chemical_classification Ethanol Chromatography Resolution (mass spectrometry) Elution Organic Chemistry Clinical Biochemistry Biochemistry High-performance liquid chromatography Analytical Chemistry Hexane chemistry.chemical_compound chemistry N-Methylaniline Enantiomer Alkyl
Zdroj:	Chromatographia. 37:487-491
ISSN:	1612-1112 0009-5893
DOI:	10.1007/bf02275784
Popis:	A high-performance liquid chromatographic method for the resolution of the enantiomers of a series ofN-alkyl-N-methylanilineN-oxides is reported. The resolutions were achieved using a Chiralcel, OD chiral stationary-phase with a mobile-phase of hexane and ethanol in varying proportions. The chromatographic order of elution of the enantiomers ofN-ethyl-N-methylanilineN-oxide was determined to be (+)-(R) before (−)-(S).
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::75c7b9981f841ba7d17eaf54839c8685 https://doi.org/10.1007/bf02275784 Zobrazit plný text záznamu Full text from SpringerLink