Novel polycyclic heterocycles. IX. Dibenz[b,f] [1,4]oxazocin-11 (12H)one, 6,11-dihydro-12H-dibenz[b,f] [1,4]oxazocine, and their derivatives

Autor:	Ervin R. Spitzmiller, Harry L. Yale
Rok vydání:	1972
Předmět:	Stereochemistry Chemistry Organic Chemistry ALUMINUM HYDRIDE chemistry.chemical_element Lithium Medicinal chemistry
Zdroj:	Journal of Heterocyclic Chemistry. 9:911-918
ISSN:	1943-5193 0022-152X
Popis:	Dibenz[b,f][1,4]oxazocin-11 (12H)one, 14, was synthesized by the dicyclohexylcarbodiimide induced cyclization of α-(o-aminophenoxy)-o-toluic acid (13). Reduction of 14 by lithium aluminum hydride gave 6,11-dihydro-12H-dibenz[b,f][1,4]oxazocine (16). Both 14 and 16 were converted to a series of 12-alkylated and -acylated derivatives. The pmr spectra of some of these compounds are discussed.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::75bff116a1605e8d6bde59c1d192bacc https://doi.org/10.1002/jhet.5570090427 Zobrazit plný text záznamu Plný text