Precursor cells of fibroblasts detected by in vitro cloning of cells from hematopoietic organs of normal and irradiated mice

Autor:	N. N. Kulagina, Yu. F. Gorskaya, A. Ya. Fridenshtein
Rok vydání:	1976
Předmět:	Cloning Pathology medicine.medical_specialty Spleen General Medicine Biology Molecular biology General Biochemistry Genetics and Molecular Biology In vitro Haematopoiesis medicine.anatomical_structure Colony formation Precursor cell medicine Bone marrow Irradiation
Zdroj:	Bulletin of Experimental Biology and Medicine. 81:765-768
ISSN:	1573-8221 0007-4888
Popis:	Colonies of fibroblasts are formed in monolayer cultures of bone marrow, spleen, and thymus cells of adult mice with an efficiency of colony formation (per 105 cells) of 2.2 for bone marrow, 0.20 for spleen, and 0.16 for thymus. On irradiation of mice with a dose of 150 R, about half of the fibroblasts colony-forming units in the bone marrow die; during the next 6 days their number falls a further fivefold, with a return to the normal level 25 days after irradiation.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::75bda0256a1e9e70beb354c008d094da https://doi.org/10.1007/bf00797159 Zobrazit plný text záznamu Full text from SpringerLink