Absence in Lymph of Capillary Permeability Factors in Traumatic Shock

Autor: Erna Lindner, H. E. Kruger, Walter Marx
Rok vydání: 1944
Předmět:
Zdroj: Experimental Biology and Medicine. 55:181-181
ISSN: 1535-3699
1535-3702
DOI: 10.3181/00379727-55-14509
Popis: It has been postulated by various investigators1 that in traumatic shock, substances increasing capillary permeability are liberated in the injured tissues. It might be expected that such substances appear in the lymph draining the traumatized region in higher concentration than in blood, In an attempt to demonstrate such factors, canine lymph was collected during shock and tested in rabbits for its effects on capillary permeability.Shock was produced by vigorous intestinal massage, peripheral circulatory collapse being verified by blood pressure, hematrocrit and autopsy observations. Lymph was obtained from a duct lying between the first and second intestinal nodes, prior to massage, and shortly before death during the period of permanently depressed blood pressure (below 70 mm Hg.). simultaneously femoral vein blood was drawn for plasma and serum samples. Permeability effects were determined in rabbits according to Menkin's method2 (intradermal injection of 0.1 cc samples of test fluids, followed by int...
Databáze: OpenAIRE