Viability of Different Types of Cells Cultivated on the Surface of Medical Electret
| Autor: | V. P. Khomutov, M. S. Morgunov, O. I. Aleksandrova, Miralda I. Blinova, Svetlana Aleksandrova |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
Stromal cell
Physics and Astronomy (miscellaneous) 020209 energy Mesenchymal stem cell Cell 02 engineering and technology engineering.material Cell morphology 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine medicine.anatomical_structure chemistry Coating Tantalum pentoxide 0202 electrical engineering electronic engineering information engineering Biophysics medicine engineering 030211 gastroenterology & hepatology Electret Bone marrow |
| Zdroj: | Technical Physics. 63:1304-1310 |
| ISSN: | 1090-6525 1063-7842 |
| DOI: | 10.1134/s1063784218090037 |
| Popis: | The effect of the electric field of a medical electret on the basis of tantalum pentoxide (Ta2O5) on the viability of human fibroblasts, multipotent mesenchymal stromal bone marrow cells, osteocytes, and chondrocytes cultivated on the surface of tantalum orthopedic implants with an electret coating was studied in vitro. Using the methods of photocolorimetic analysis and scanning electron microscopy, difference in the metabolic activity and cell morphology, in the character of the cell attachment to the implants and distribution by their surface, associated with the value and character of the electric charge distribution on the surface of these implants and the type of cellular test systems, were detected. Unclear mechanisms of the effect of the electric field of medical electrets on the functional activity of different types of the organism cell and tissues dictate the need for further experimental developments and fundamental studies in this field. |
| Databáze: | OpenAIRE |
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