Three-dimensional black-blood T 2 mapping with compressed sensing and data-driven parallel imaging in the carotid artery
| Autor: | Ammara Usman, Scott Reid, Jonathan H. Gillard, Kevin F. King, Jianmin Yuan, Andrew J. Patterson, Martin J. Graves |
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| Rok vydání: | 2017 |
| Předmět: |
medicine.medical_specialty
medicine.diagnostic_test Intraclass correlation business.industry Biomedical Engineering Biophysics Magnetic resonance imaging Repeatability Imaging phantom 030218 nuclear medicine & medical imaging Correlation 03 medical and health sciences 0302 clinical medicine Concordance correlation coefficient Compressed sensing medicine Radiology Nuclear Medicine and imaging Radiology Parallel imaging Nuclear medicine business 030217 neurology & neurosurgery Mathematics |
| Zdroj: | Magnetic Resonance Imaging. 37:62-69 |
| ISSN: | 0730-725X |
| DOI: | 10.1016/j.mri.2016.11.014 |
| Popis: | Purpose To develop a 3D black-blood T 2 mapping sequence with a combination of compressed sensing (CS) and parallel imaging (PI) for carotid wall imaging. Materials and methods A 3D black-blood fast-spin-echo (FSE) sequence for T 2 mapping with CS and PI was developed and validated. Phantom experiments were performed to assess T 2 accuracy using a Eurospin Test Object, with different combination of CS and PI acceleration factors. A 2D multi-echo FSE sequence was used as a reference to evaluate the accuracy. The concordance correlation coefficient and Bland-Altman statistics were calculated. Twelve volunteers were scanned twice to determine the repeatability of the sequence and the intraclass correlation coefficient (ICC) was reported. Wall-lumen sharpness was calculated for different CS and PI combinations. Six patients with carotid stenosis > 50% were scanned with optimised sequence. The T 2 maps were compared with multi-contrast images. Results Phantom scans showed good correlation in T 2 measurement between current and reference sequence (r = 0.991). No significant difference was found between different combination of CS and PI accelerations (p = 0.999). Volunteer scans showed good repeatability of T 2 measurement (ICC: 0.93, 95% CI 0.84–0.97). The mean T 2 of the healthy wall was 48.0 ± 9.5 ms. Overall plaque T 2 values from patients were 54.9 ± 12.2 ms. Recent intraplaque haemorrhage and fibrous tissue have higher T 2 values than the mean plaque T 2 values (88.1 ± 6.8 ms and 62.7 ± 9.3 ms, respectively). Conclusion This study demonstrates the feasibility of combining CS and PI for accelerating 3D T 2 mapping in the carotid artery, with accurate T 2 measurements and good repeatability. |
| Databáze: | OpenAIRE |
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