An Efficient Synthesis of 2-[(4-Amino∼1,2-dihyro-2-oxo-1- pyrimidinyl)methoxyi-l,3-propanediyl-di-L-valinate an Anti-cytomegalovirus Agent

Autor: Martha Rodriguez, Taj Naseree, Tracy Scott, Roy Flanagan, Nabih Ghal, Barbara Johnston, Lilia M. Beauchamp
Rok vydání: 1995
Předmět:
Zdroj: Nucleosides and Nucleotides. 14:1591-1600
ISSN: 0732-8311
DOI: 10.1080/15257779508009494
Popis: A novel synthesis of 1-(β-D-pentopyranosyl)pyridinethione nucleosides utilizing pyridine-2(1H)-thiones and α-bromoxylose or β-bromoarabinose triacetate as starting components is described. The free nucleosides were tested for their potential activity against HIV and different types of tumor virus.
Databáze: OpenAIRE