Chromium Picolinate did not Effect on the Proliferation and Differentiation of Myoblasts
| Autor: | T F Lien, M C Tsa |
|---|---|
| Rok vydání: | 2007 |
| Předmět: |
medicine.medical_specialty
Myoblast proliferation Hexokinase General Veterinary Myogenesis Aldolase A chemistry.chemical_element Biology musculoskeletal system chemistry.chemical_compound Chromium Endocrinology chemistry Internal medicine medicine biology.protein Myocyte Animal Science and Zoology Creatine kinase C2C12 |
| Zdroj: | American Journal of Animal and Veterinary Sciences. 2:79-83 |
| ISSN: | 1557-4555 |
| Popis: | This experiment is conducted in vitro to investigate trivalent chromium picolinate affects the proliferation and differentiation of myoblasts. A myoblasts cell line (C2C12) from rats was used in the experiment. These were randomly divided into the control group, the Pic group (50ppb picolinate) and the CrPic group (50ppb chromium picolinate). The differentiation of myoblasts reveals that the number of differentiated myotubes, creatine kinase (CK) activity and the aldolase (ALB) activity do not differ among the three groups (P > 0.05). The activity of hexokinase in the CrPic and Pic groups clearly exceeds that in the control group (P 0.05). Myoblast proliferation was the same across the three groups (P > 0.05), and the quantity of DNA in the control group exceeded that in the Pic group (P < 0.05). The experiment indicated that 200ppb chromium picolinate did not influence the proliferation and differentiation of myoblasts. |
| Databáze: | OpenAIRE |
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