Synthesis of polyfluoroalkylated α-Aminophosphonic/thiophosphonic acids derivatives
| Autor: | Yuliya V. Rassukana, Olena I. Kyselyova, Ivanna P. Yelenich, Kateryna A. Zamulko, Petro P. Onys’ko |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
010405 organic chemistry
Chemistry Stereochemistry Organic Chemistry Substituent 010402 general chemistry 01 natural sciences Biochemistry 0104 chemical sciences Inorganic Chemistry chemistry.chemical_compound medicine Environmental Chemistry Fotemustine Organic chemistry Physical and Theoretical Chemistry medicine.drug |
| Zdroj: | Journal of Fluorine Chemistry. 185:191-196 |
| ISSN: | 0022-1139 |
| DOI: | 10.1016/j.jfluchem.2016.03.014 |
| Popis: | Convenient synthetic approaches for previously unknown α-aminotetrafluoropropylphosphonic/thiophosphonic acids derivatives were developed based on readily accessible N -(α-hydroxytetrafluoropropyl)carbamates. Synthesis of analogs of marketed anticancer agent Fotemustine bearing polyfluoroalkyl group instead of methyl substituent, has been performed. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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