Investigation of magnetic nanoparticle targeting in a simplified model of small vessel aneurysm
| Autor: | S.N. Mirzababaei, Mofid Gorji-Bandpy, M. Baou, Tahereh B. Gorji, Nasser Fatouraee |
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| Rok vydání: | 2017 |
| Předmět: |
010302 applied physics
Diffraction Ferrofluid Materials science Magnetometer Scanning electron microscope Nanoparticle 02 engineering and technology equipment and supplies 021001 nanoscience & nanotechnology Condensed Matter Physics 01 natural sciences Electronic Optical and Magnetic Materials Magnetic field law.invention Nuclear magnetic resonance law 0103 physical sciences Magnetic nanoparticles Fourier transform infrared spectroscopy 0210 nano-technology human activities |
| Zdroj: | Journal of Magnetism and Magnetic Materials. 426:126-131 |
| ISSN: | 0304-8853 |
| DOI: | 10.1016/j.jmmm.2016.11.044 |
| Popis: | An in simulacra study was conducted to investigate the capture efficiency (CE) of magnetic nanoparticles (MNPs) in aneurysm model, under the effect of a bipolar permanent magnetic system positioned at the vicinity of the model vessel. The bipolar magnetic system with an active space of 9 cm was designed by FEMM software. The MNPs were magnetite nanoparticles synthesized by the hydrothermal method which were characterized by X-ray diffraction, Fourier transform infrared spectroscopy, scanning electron microscope and magnetometer measurements. Ferrofluid velocity, magnetic field strength, and aneurysm volume all proved to be important parameters which affect the capturing of MNPs. Overall, the results of this in simulacra study confirmed the effectiveness of magnetic targeting for possible aneurysm embolization. |
| Databáze: | OpenAIRE |
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