Metastatic Mucinous Adenocarcinoma of the Prostate: Case Report and a Review of the Literature
| Autor: | N. Kadri, M. Darfaoui, I. Zaytoune, A. Sabiq, A. El Omrani, M. Khoucha, M. Oubihi, A. Azrag, M. A. Lakmichi, M. S. Moudouni, Z. Dahami, I. Sarf |
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| Rok vydání: | 2022 |
| Předmět: | |
| Zdroj: | Scholars Journal of Medical Case Reports. 10:937-939 |
| ISSN: | 2347-6559 2347-9507 |
| Popis: | We report the case of a 47 years old man with a first-degree familial history of prostate cancer in the father and breast cancer in the sister. Our patient presented an irritative urinary syndrome for 7 months; the clinical examination revealed a stony prostate on rectal examination, initial PSA was 1ng /ml, pelvic MRI showed an enlarged prostate measuring 65*60*45mm, with irregular contours and a median lobe protruding into the bladder lumen. The tumor was globally responsible for a capsular effraction with infiltration of the posterior bladder wall in front and at the base of the seminal vesicles behind. The patient underwent a transurethral resection of the prostate (TURP) with anatomopathological and immuno-histochemical studies showing a profile in favor of a mucinous prostatic adenocarcinoma. The tumor markers angiotensin converting enzyme (ACE) and cancer antigen 19-9 (CA19.9) were normal at 9.71 ng/ml and 22.96 IU/ml respectively. The extension workup showed metastatic lesions in the lung and skin (positive skin biopsy). The total colonoscopy was normal. Clinically, the patient presented with a WHO performance status at 3 and could not receive chemotherapy. He was put under symptomatic treatment and passed away one month later. The series reported in the literature are few; nevertheless, it seems that the prognosis of mucinous adenocarcinoma is considered to be comparable if not favorable to conventional adenocarcinoma even though it has been believed to be more aggressive in the past. |
| Databáze: | OpenAIRE |
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