Chiral 1,3-Oxazolidines as the Ligands for the Enantioselective Addition of Diethylzinc to Aryl Aldehydes

Autor:	N. N. Joshi, K. R. K. Prasad
Rok vydání:	2003
Předmět:	chemistry.chemical_compound chemistry Aryl Enantioselective synthesis chemistry.chemical_element Organic chemistry General Medicine Zinc Diethylzinc Catalysis
Zdroj:	ChemInform. 34
ISSN:	1522-2667 0931-7597
DOI:	10.1002/chin.200316026
Popis:	Various 1,3-oxazolidines have been prepared from norephedrine and aldehydes/ketones and the corresponding zinc amides prepared in situ have been utilized as catalysts for the enantioslective addition of diethylzinc to aryl aldehydes. Good enantioselectivities (73-85%) and consistent product configuration are realized in all the cases examined. A mechanism has been proposed that can account for the stereochemical outcome.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::7577c3d2d592a19507df6d880f8069e1 https://doi.org/10.1002/chin.200316026 Zobrazit plný text záznamu Plný text