A comparative biopharmaceutical study of modified-release tamsulosin capsules

Autor:	S. E. Kondakov, V. K. Alekseev, E. E. Lazareva, N. A. Uvarov, E. V. Blynskaya
Rok vydání:	2013
Předmět:	Biopharmaceutical Pharmacokinetics In vivo Tamsulosin Chemistry medicine Distribution (pharmacology) General Chemistry Absorption (skin) Pharmacology Bioequivalence medicine.drug Bioavailability
Zdroj:	Moscow University Chemistry Bulletin. 68:167-170
ISSN:	1935-0260 0027-1314
DOI:	10.3103/s0027131413030061
Popis:	A comparative biopharmaceutical study of modified-release tamsulosin capsules and Omnic preparation has been performed. The pharmacokinetic characteristics of the preparations have been assessed and the relative bioavailability has been determined. In vivo experiments have shown that absorption, distribution, metabolism, and clearance of tamsulosin administered as modified-release tamsulosin capsules (0.4 mg) or Omnic capsules (0.4 mg) are identical and, therefore, the formulations are biologically equivalent.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::75617d88e9fa62efbad83c3105d68257 https://doi.org/10.3103/s0027131413030061 Zobrazit plný text záznamu Full text from SpringerLink