Fasting Glucose in Acute Myocardial Infarction

Autor: Abeer Suleiman, Walter Markiewicz, Doron Aronson, Mahmoud Suleiman, Haim Hammerman, Rafael Beyar, Michael Kapeliovich, Yoram Agmon
Rok vydání: 2007
Předmět:
Zdroj: Diabetes Care. 30:960-966
ISSN: 1935-5548
0149-5992
DOI: 10.2337/dc06-1735
Popis: OBJECTIVE—Elevation of blood glucose is a common metabolic disorder among patients with acute myocardial infarction (AMI) and is associated with adverse prognosis. However, few data are available concerning the long-term prognostic value of elevated fasting glucose during the acute phase of infarction. RESEARCH DESIGN AND METHODS—We prospectively studied the relationship between fasting glucose and long-term mortality in patients with AMI. Fasting glucose was determined after an ≥8 h fast within 24 h of admission. The median duration of follow-up was 24 months (range 6–48). All multivariable Cox models were adjusted for the Global Registry of Acute Coronary Events (GRACE) risk score. RESULTS—In nondiabetic patients (n = 1,101), compared with patients with normal fasting glucose ( CONCLUSIONS—Fasting glucose is a simple robust tool for predicting long-term mortality in nondiabetic patients with AMI. Fasting glucose provides incremental prognostic information when added to the GRACE risk score and left ventricular ejection fraction. Fasting glucose is not a useful prognostic marker in patients with diabetes.
Databáze: OpenAIRE