Efficient synthesis of a 7-azabicyclo[2.2.1]heptane based GlyT1 uptake inhibitor

Autor:	William Frietze, Jeffrey S. Albert, Lindsay Hinkley, William E. Palmer, Hui Xiong, Donald Andisik, Jeffrey G. Varnes, Glen Ernst, Chris Allan Veale
Rok vydání:	2010
Předmět:	Heptane chemistry.chemical_compound chemistry Organic Chemistry Drug Discovery Electrophile Organic chemistry Biochemistry
Zdroj:	Tetrahedron Letters. 51:6741-6744
ISSN:	0040-4039
Popis:	An efficient synthetic route based on generation and subsequent electrophilic reaction of a Boc-protected azabicyclo[2.2.1]heptane anion to prepare a potent GlyT1 uptake inhibitor (1) is described.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::755b63efa5db4f1809f96e8397cf4174 https://doi.org/10.1016/j.tetlet.2010.10.079 Zobrazit plný text záznamu Full Text from ScienceDirect