Oxidation of dextran using H2O2 and NaClO/NaBr and their applicability in iron chelation
| Autor: | Jing-wen Yang, Hao Wu, Xue-qin Hu, Ding-cong Shang-guan, Qi-meng Lu, Hong-bin Zhang |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
food.ingredient
medicine.medical_treatment chemistry.chemical_element Iron supplement 02 engineering and technology Polysaccharide Biochemistry Iron chelation 03 medical and health sciences chemistry.chemical_compound food Structural Biology medicine Chlorine Molecule Chelation Molecular Biology 030304 developmental biology chemistry.chemical_classification 0303 health sciences Chemistry Food additive General Medicine 021001 nanoscience & nanotechnology Dextran 0210 nano-technology Nuclear chemistry |
| Zdroj: | International Journal of Biological Macromolecules. 144:615-623 |
| ISSN: | 0141-8130 |
| DOI: | 10.1016/j.ijbiomac.2019.12.104 |
| Popis: | The structural modification of polysaccharides directly affects their physicochemical properties and applications. Dextran, a chained polysaccharide, consists of multiple d -glucose molecules with repetitive structures. In this study, the physicochemical properties of oxidized dextran (DO) at different concentrations of NaClO/NaBr and H2O2 were compared. The results showed that NaClO/NaBr oxidation is more conducive to the formation of carboxyl groups. Oxidized dextran with NaClO/NaBr (DOB) showed good iron (III) chelating ability, and the DOB‑iron (III) complex (DOBIC) had an iron content of 28.31%. According to structural analysis, NaClO/NaBr (2 g/100 g of active chlorine) and H2O2 (4 g/100 g), respectively, oxidize the C1 and C2 hydroxyl groups of dextran to carboxyl groups and open the ring when DO and iron have the strongest chelation ability. The complex is indeed a chelate iron complex, and iron core is composed of iron oxyhydroxide or the β-FeOOH mineral polymorph. These results indicate that DOBIC is expected to be a good iron supplement or food additive to strengthen iron. |
| Databáze: | OpenAIRE |
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