| Autor: |
Maria Christina Cox, Luigi Marcheselli, Giorgia Scafetta, Carlo Visco, Stefan Hohaus, Ombretta Annibali, Gerardo Musuraca, Alberto Fabbri, Maria Cantonetti, Sabrina Pelliccia, Robel Papotti, Luigi Petrucci, Monica Tani, Roberta Battistini, Annalisa Arcari, Stefano Luminari, Gianluca Lopez, Eleonora Alma, Livio Pupo, Giuseppe Carli, Francesco Marchesi, Francesca Re, Stefania Scarpino, Emanuele D’amore, Luigi M Larocca, Antonella Bianchi, Giuseppina Pepe, Fiammetta Natalino, Paola Anticoli-Borza, Natalia Cenfra, Alessandro Andriani, Elisabetta Abruzzese, Cristiano Tesei, Lorenzo Leoncini, Silvia Asioli, Luigi Ruco, Arianna Di Napoli |
| Rok vydání: |
2022 |
| Předmět: |
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| Popis: |
PURPOUSE: to assess the clinicopathologic features of a poorly defined subset of diffuse large b-cell lymphoma, which is characterized by the secretion of an IgM paraprotein (IgMs-DLBCL). EXPERIMENTAL DESIGN: multicentre, retrospective, and comparative study to analyse with an integrated diagnostic approach the IgMs-DLBCL subset.RESULTS: Overall, 650 DLBCL were enrolled: 102 had an associated serum IgM and 56 other paraproteins (OP), the remaining 492 cases were the reference group (REF). IgMs-DLBCL were characterized by older age, advanced stage, dissemination to extra-nodal organs, elevated LDH and poor PS. As a result, the majority of IgMs had a high IPI, NCC-IPI and CNS-IPI score (p |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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