Clinical Risk Stratification of Pulmonary Embolism to Support the Development of a Pulmonary Embolism Response Team (PERT) at a Tertiary Referral Hospital

Autor: Emmet O'Brien, Robyn Poole, Ross K. Morgan, Ronan Lee, Patricia Houlihan, Patrick Kerr, Michelle Lavin, Michael Lee, Brendan McAdam
Rok vydání: 2020
Předmět:
Zdroj: Pulmonary embolism.
Popis: Introduction: The simplified Pulmonary Embolism Severity Index (sPESI) risk stratifies patients with PE. Current guidelines support the establishment of PERT to inform treatment decisions, educate and guide local policy in PE management. The objective of this study was to determine the number of patients with PE that may benefit from review by PERT and/or consideration of catheter directed thrombolysis (CDT) in our institution. Methods: A retrospective analysis of all cases of PE diagnosed in 2018 at our institution was undertaken. Data in relation to sPESI score, cardiac biomarkers and evidence of right heart strain by echocardiogram/CT analysis was gathered. Results: PE was identified in 158/1121 (14.1%) CT Pulmonary Angiograms performed at our institution in 2018. Data was missing in 3 cases; 155 cases were included in analysis. Two cases received systemic thrombolysis (1 intermediate and 1 high risk). A significant proportion (79%) of cases had a high sPESI – categorised as intermediate or high risk PE. Most patients (70%) were managed by a primary physician without specialist training in cardiology or respiratory medicine. CDT may be considered in 26 (17%) of PE cases. Conclusion: Application of clinical risk stratification in our institution supports the establishment of PERT to promote guideline-based care, provide clinical input for PE treatment and guide uptake of novel therapies in select patients with PE.
Databáze: OpenAIRE