Electrochemical Detection of Steroid Hormones Using a Nickel-Modified Glassy Carbon Electrode

Autor:	Michael Partridge, Nigel Guerra, Grace W. Muna, Holly Garner, Hala Sirhan, Bridget VerVaet
Rok vydání:	2014
Předmět:	Detection limit Materials science Chromatography Fouling Dynamic range medicine.medical_treatment chemistry.chemical_element High-performance liquid chromatography Analytical Chemistry Steroid Nickel chemistry Electrode Electrochemistry medicine Figure of merit
Zdroj:	Electroanalysis. 26:2145-2151
ISSN:	1040-0397
Popis:	This paper demonstrates the development of an analytical method for detecting steroid hormones by coupling HPLC to electrochemical detection, using a nickel-modified glassy carbon electrode. The method was evaluated in terms of sensitivity, linear dynamic range, limit of detection, and response stability. The developed method exhibited good figures of merit for the steroid hormones studied with no evidence of electrode fouling. As an example, the limit of detection (S/N=3) for E3 was 0.10 µM and the response precision (n=5) was 0.6 %. The application of the method for the analysis of a real river water sample is demonstrated.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::751b2c328e9a0a5f889f2d4e63839be5 https://doi.org/10.1002/elan.201400361 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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