| Popis: |
Recent development of visible light Optical Coherence Microscopy (i.e. Optical Coherence Tomography employing high numerical aperture Objective) has pushed the axial/transverse resolution limit to < 2 μm within tissues. Here, a fiber-based visible light Fourier domain (FD) Optical Coherence Microscopy system is presented, employing a 10x water immersion objective to achieve higher transverse resolution and reduced specular reflection when imaging human skin in vivo, using ~ 1-2 mW of incident power. Though with limited penetration depth, we demonstrated its application for in vivo imaging of human skin, and further measured the thicknesses of epidermis and dermo-epidermal junction. Furthermore, the total attenuation coefficient of the skin tissues was also estimated across epidermis and dermis. |
