Acute Placental Insufficiency Two Weeks After an Asymptomatic COVID-19 Maternal Infection: The Deleterious Effects of The SARS-Cov-2 Placentitis Associated with B.1.617.2 (Delta) Variant. Report of Two Cases

Autor: Loredana Delle Chiaie, Ilona Stolpner, Katrin Baltz-Ghahremanpour
Rok vydání: 2022
DOI: 10.21203/rs.3.rs-1343858/v1
Popis: We present two cases of acute severe placental insufficiency in the late second trimester and in the third trimester of pregnancy, emerging within 14 days following a mild COVID-19 (Delta variant) disease in two not vaccinated healthy women with hitherto unremarkable pregnancies. The pathognomonic histopathological findings and the RT-PCR positivity of the placenta suggest the SARS-CoV-2 placentitis as the possible cause of the severe fetal distress. At present, propagation of vaccination and a strict feto-maternal surveillance in the first weeks after maternal infection seem to be the only way to protect the gestation from the risks of acute placental insufficiency associated with the SARS-CoV-2 infection.
Databáze: OpenAIRE