| Popis: |
BACKGROUND: Exercise-induced laryngeal obstruction (EILO) causes wheezing and dyspnoea on exertion and can co-exist with asthma, complicating management of this patient group. Respiratory symptoms may discourage patients from exercising or engaging in strenuous activities although physical conditioning might improve their symptoms, particularly in untrained individuals. AIM: To investigate the feasibility of high-intensity low-volume training of patients with EILO and to determine if respiratory symptoms and degree of laryngeal obstruction improves with physical conditioning in this patient group. METHODS: Untrained patients with verified EILO, some with concurrent asthma, were randomised to 8 weeks of either control: continuing daily activities as usual or training: high-intensity low-volume indoor cycling three times a week supervised by an instructor. Patients with asthma continued their regular asthma medication. Training consisted of 2-4 sets of five one-minute intervals of 30 seconds at light intensity, 20 seconds at moderate intensity and 10 seconds at ≥90% of maximal heart rate. Before and after the training period ergospirometry was performed in duplicate, one of which included simultaneous endoscopic recording of laryngeal obstruction, and Borg Rate of Perceived Exertion was recorded. RESULTS: At the time of writing, 10 patients completed the study. All patients in the training group completed the training without adverse events, whereas two patients in the control group dropped out due to asthma exacerbation and depression, respectively. Inclusion ends in May 2016 and results are expected to be ready for presentation in September 2016. |
