An on-chip biosensor based on supercritical angle fluorescence

Autor: Pieter Neutens, Pol Van Dorpe, Finub James Shirley, Tim Steylaerts
Rok vydání: 2021
Předmět:
Zdroj: Photonic Diagnosis, Monitoring, Prevention, and Treatment of Infections and Inflammatory Diseases 2021.
Popis: Supercritical angle fluorescence (SAF) is a surface sensitive detection mechanism that has been used to perform rapid, sensitive detection of biomolecules. However, the SAF biosensors that have been demonstrated so far have been either bulky and expensive or small and affordable while sacrificing on sensitivity . We present a novel interference based SAF biosensor technology that has the potential to be fast, small, inexpensive and mass manufacturable while being as sensitive as the current gold standard. This technology can therefore create biosensors in a wide range of form factors, from large, complex high multiplex devices to small handheld point of care solutions.
Databáze: OpenAIRE