Synthesis and Transmembrane Transport Studies of Lipophilic Adenosine 5′-Triphosphate Derivatives

Autor:	François André, Aline Bluzat, Annett Kreimeyer, Catherine Gouyette, Tam Huynh-Dinh
Rok vydání:	1999
Předmět:	chemistry.chemical_classification Liposome Vesicle Prodrug Membrane transport Biochemistry Adenosine Membrane Enzyme chemistry Genetics medicine lipids (amino acids peptides and proteins) Myristoylation medicine.drug
Zdroj:	Nucleosides and Nucleotides. 18:995-999
ISSN:	0732-8311
Popis:	The preparation of acyl adenosine 5′-triphosphates as potential membrane permeable prodrugs is presented. The interaction of myristoyl- and cholesteryloxy-carbonyl-ATP with liposomes as model membranes and the release of ATP inside these vesicles was investigated using an enzymatic assay as well as 31P-NMR spectroscopy.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::74ef77d7634924ba25be869f7d6a065f https://doi.org/10.1080/15257779908041627 Zobrazit plný text záznamu