Cytologic Features of Pleural Effusion in Apocrine Sweat Gland Carcinoma

Autor: Yoshiro Ebihara, Myota Miura, Yoko Maeda, Yoko Miyake, Masako Otani, Motoshige Kudo
Rok vydání: 2001
Předmět:
Zdroj: Acta Cytologica. 45:74-78
ISSN: 1938-2650
0001-5547
DOI: 10.1159/000327190
Popis: BACKGROUND: Carcinoma arising in the apocrine sweat glands is very rare, and there are few reports of the cytologic features. We encountered a case of metastatic apocrine carcinoma in a pleural effusion. CASE: A 46-year-old male had a dark reddish nodule in the right axillary region that was diagnosed as apocrine carcinoma of skin appendage origin. Three years after wide resection and chemotherapy, widespread metastases developed with a massive pleural effusion. Needle aspiration fluid cytology contained clusters of adenocarcinoma. Some tumor cells had abundant cytoplasm or periodic acid‐Schiff-positive, coarse granules. Decapitation secretion was occasionally found on the cell surface. Immunohistochemically, the tumor cells were often positive for BRST-2 and BRST-3. CONCLUSION: Cytologic features of metastatic apocrine sweat gland carinoma show some characteristics of adenocarcinoma. Moreover, its definitive diagnosis in a pleural effusion can be made because of retaining the characteristics of apocrine sweat gland. (Acta Cytol 2001;45:74‐78)
Databáze: OpenAIRE