Chemical copying of connectivity
Autor: | Lars Henning Eckardt, Kai Naumann, Günter von Kiedrowski, Wolf Matthias Pankau, Michael Rein, Markus Schweitzer, Norbert Windhab |
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Rok vydání: | 2002 |
Předmět: | |
Zdroj: | Nature. 420:286-286 |
ISSN: | 1476-4687 0028-0836 |
DOI: | 10.1038/420286a |
Popis: | Three-dimensional DNA nanoscaffolds such as supramolecular tetrahedra can self-assemble from tris-oligonucleotidyls — synthetic three-armed building blocks in which three identical or non-identical short DNA sequences are connected by a tris-linking backbone1,2. Here we show that the connectivity information contained in these building blocks can be copied by using template-directed tris-linking. This finding is a crucial step towards the replication of nanoarchitectures that are based on tris-oligonucleotidyls and to the realization of artificially self-replicating systems on a nanometre scale. |
Databáze: | OpenAIRE |
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