Herbology, Antibacterial and Antihaemorrhagic Effect of Allium sativum Linn (Lilliaceae) Extracts against Bacterial Meningitis Pathogens

Autor: Abdullahi Attah Alfa, O Omotoso, Umar Sabdat Unoyiza, Yahaya Junaidu, Kokori Bajeh Tijani
Rok vydání: 2021
Předmět:
Zdroj: Asian Journal of Advanced Research and Reports. :10-18
ISSN: 2582-3248
DOI: 10.9734/ajarr/2021/v15i130353
Popis: Bacterial Meningitis pathogen (BMP) causes cellular hemorrhagic sepsis, metabolic, endocrine and neurologic disorders in human systems. This burden of the disease is highest in the developing countries and especially in the immunity compromised rural populations in Sub-Saharan Africa. The A. sativum bulb extracts (JEAS, EEAS and AEAS) contain valuable pharmacologically active principles for antihaemorrhagic and antibacterial properties against bacterial meningitis pathogens. It extracts were evaluated in Wistar rats to provide scientific basis for ethnomedicinal uses. The phytochemical screening was conducted using standard method prescribed. Anti-haemorrhagic activity was evaluated using sterilized blade lancet to cut 2mm long and 2mm deep in the rat groin model. The coagulative effects of time were significantly at P
Databáze: OpenAIRE