Efficacy of electrochemically activated water solution in gingivitis treatment
Autor: | Van Huy Pham, Thi Thu Phuong Nguyen, Van Nhon Bui, Truong Nhu Ngoc Vo, Thien Chu-Dinh, Khanh Hoang Nguyen, Quynh Anh Le, Duc Long Duong, Dinh-Toi Chu, Minh Son Tong |
---|---|
Rok vydání: | 2018 |
Předmět: |
medicine.medical_specialty
Treated group business.industry medicine.medical_treatment Disinfectant Treatment outcome Significant difference Bleeding on probing Pharmaceutical Science 02 engineering and technology 010402 general chemistry 021001 nanoscience & nanotechnology 01 natural sciences Gastroenterology 0104 chemical sciences Clinical study Gingivitis Internal medicine medicine medicine.symptom 0210 nano-technology business Pharmacology Toxicology and Pharmaceutics (miscellaneous) Saline |
Zdroj: | Journal of Pharmaceutical Investigation. 49:323-329 |
ISSN: | 2093-6214 2093-5552 |
DOI: | 10.1007/s40005-018-00419-7 |
Popis: | Mouthwash is one of the most commonly oral healthcare products for prevention and treatment of gum diseases. Dr. ECA is a disinfectant solution manufactured by a Vietnamese company and has been licensed for oral healthcare, but its effect on gingivitis is still unclear. To evaluate the effectiveness of this product in the treatment of gingivitis, we conducted a clinical study in 60 students diagnosed with gingivitis to compare the results of gingivitis treatment using Dr. ECA and a control mouthwash (a demonstrated anti-gingivitis product). The data showed that in the treated group, the rate of good Gingivitis Index (GI) before treatment was 46.67%, but after 2 and 4 weeks of using Dr. ECA that rate was increased to 96.67% and 100%, respectively. The percentage of patients with bleeding on probing was 63.33% but declined sharply after 2 weeks of treatment to 6.67%, and further reduced to 3.33% after 4 weeks of treatment. The treatment outcomes in were similar in the Dr. ECA treated group and control one with no statistically significant difference. Our results suggest that the electrolyte saline solution Dr. ECA is effective in treating gingivitis. Its effects are similar to other mouthwash products that had been approved and marketed. |
Databáze: | OpenAIRE |
Externí odkaz: |