Relationship between exercise-induced systemic inflammatory like reaction and racing performance in endurance horses
| Autor: | Isabelle Caudron, Dominique Votion, Charlotte Sandersen, Jean-Philippe Lejeune, Didier Serteyn, Thierry Franck, Justine Ceusters |
|---|---|
| Rok vydání: | 2012 |
| Předmět: |
medicine.medical_specialty
Physiology Veterinary (miscellaneous) Endocrinology Diabetes and Metabolism Lymphocyte Biophysics Inflammation Biochemistry Physiology (medical) Internal medicine medicine Orthopedics and Sports Medicine biology business.industry Elastase Horse medicine.anatomical_structure Endocrinology Myeloperoxidase Concomitant Plasma concentration Immunology Absolute neutrophil count biology.protein medicine.symptom business |
| Zdroj: | Comparative Exercise Physiology. 8:213-218 |
| ISSN: | 1755-2559 1755-2540 |
| Popis: | Endurance race induces a rise of serum creatine kinase (CK) activity and a systemic inflammatory like response characterised by an increase of neutrophil counts, plasma and muscle myeloperoxidase (MPO) and elastase (ELT) concentrations in horses. Horses performing the same standardised exercise test do not respond with the same magnitude of inflammatory reaction. The aim of the present study was to measure the total neutrophil count, the ratio neutrophil:lymphocyte, the MPO and ELT plasma concentrations and concomitant increases of serum CK activities in competing endurance horse and to relate these results to their race performance. Twenty one horses participating in a 120 km 4 star endurance race recruited on a voluntary basis finished the race with a mean speed ranging from 13.1 to 19.8 km/h. Blood was taken the day before the race and two hours after the race. Mean values of neutrophil counts, ratio neutrophil:lymphocyte, plasma MPO and ELT concentrations and serum CK activities after the race were significantly higher than the pre-race values. There was no correlation between neutrophil counts, MPO, ELT or CK and the mean speed of the horses during the race except for the ratio neutrophil:lymphocyte where a significant negative correlation was observed. These results showed that systemic responses induced by strenuous exercise such as an endurance race is not clearly related to performance but also to horse-related factors, such as intrinsic capacity or training. |
| Databáze: | OpenAIRE |
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