Sequential 1,3-dipolar cycloaddition-palladium catalysed cyclisation. A powerful new tactical combination

Autor:	Ronald Grigg, Thomas Coulter
Rok vydání:	1991
Předmět:	Bicyclic molecule Chemistry Organic Chemistry Azomethine ylide chemistry.chemical_element Biochemistry Combinatorial chemistry Cycloaddition Catalysis chemistry.chemical_compound Drug Discovery 1 3-Dipolar cycloaddition Imide Palladium
Zdroj:	Tetrahedron Letters. 32:1359-1362
ISSN:	0040-4039
DOI:	10.1016/s0040-4039(00)79667-5
Popis:	A new flexible tactical combination of a 1,3-dipolar cycloaddition of an in situ generated azomethine ylide followed by a palladium catalysed cyclisation is described. The two reactions can be carried out as a 1 pot procedure if desired. Four new stereocentres and two new rings are created by this strategy.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::74834b46522f8a28d0cd61ee95498bec https://doi.org/10.1016/s0040-4039(00)79667-5 Zobrazit plný text záznamu