IMMUNOFLUORESCENCE AS A DIAGNOSTIC TOOL FOR ORAL LICHEN PLANUS
| Autor: | Malu Bastos Souza Cerqueira, Luciana Maria Pedreira Ramalho, Sérgio Arruda, Leonardo De Araújo Melo, Manoela Carrera Martinez Cavalcante Pereira |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
medicine.diagnostic_test business.industry Connective tissue Physical examination medicine.disease Immunofluorescence Dermatology Pathology and Forensic Medicine medicine.anatomical_structure Prednisone Tongue Biopsy medicine Radiology Nuclear Medicine and imaging Dentistry (miscellaneous) Surgery Oral lichen planus Oral Surgery Chronic Inflammatory Infiltrate business medicine.drug |
| Zdroj: | Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology. 130:e196 |
| ISSN: | 2212-4403 |
| DOI: | 10.1016/j.oooo.2020.04.409 |
| Popis: | A 40-year-old female patient without systemic diseases and without the use of medication presented complaints of painful and bleeding wounds on the mouth. On physical examination, multiple bleeding ulcers on the tongue, lip, and jugal mucosa were observed, some with fibrinopurulent pseudomembrane. Laboratory tests excluded autoimmune diseases, venereal diseases, and anemias. Excisional biopsy was performed to exclude the diagnosis of bullous lesions. Anatomohistopathologic examination demonstrated areas of ulcerated connective tissue with chronic inflammatory infiltrate. Immunofluorescence indicated the presence of fibrinogen deposits, closing the diagnosis as oral lichen planus. After the biopsy, the patient took 8 months to return to the service. At this moment, she presented with the same oral condition plus pruritic, violaceous lesions on the skin with a predilection for upper and lower limbs. Treatment with prednisone 60 mg/d was instituted, and the patient is in clinical follow-up. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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