Analysis of the Left Ventricular Contractile Reserve Using End-systolic Pressure-Volume Relation (ESPVR) in Idiopathic Dilated Cardiomyopathy: Its Correlation with Pathologic Findings
| Autor: | Se-Joong Rim, Jong-Won Ha, Young Seop Byeon, Seung Yun Cho, Young Ro Yoon, Sung Soon Kim, Joo Hyun Seok, Moon Hyung Lee, Won Heum Shim, Namsik Chung, Yangsoo Jang, Nam Ho Lee, Sang-Ho Cho, Jae Woo Shin |
|---|---|
| Rok vydání: | 1999 |
| Předmět: |
medicine.medical_specialty
medicine.diagnostic_test business.industry medicine.medical_treatment Balloon catheter Hemodynamics Dilated cardiomyopathy Doppler echocardiography medicine.disease Inferior vena cava Contractility medicine.vein Internal medicine Idiopathic dilated cardiomyopathy medicine Cardiology business Cardiac catheterization |
| Zdroj: | Korean Circulation Journal. 29:751 |
| ISSN: | 1225-164X |
| DOI: | 10.4070/kcj.1999.29.7.751 |
| Popis: | Background:Left ventricular (LV end-systolic pressure volume relation (ESPVR is considered as a load independent contractile index. However, its application in human beings has been limited by the difficulty in the accurate real time measurement of the LV volume changes. With introduction of the echocardiographic automatated edge detection method, on-line generation of multiple LV pressure volume-loops has become possible to assess ESPVR. This study was performed to investigate the correlation of the degree of myocardial damages with myocardial contractility and contractile reserve assessed by ESPVR as a surrogate of contractility index. Methods:Studies were attempted in ten patients with idiopathic dilated cardiomyopathy. Baseline two-dimensional and Doppler echocardiography, cardiac catheterization for hemodynamicassessment and endomyocardial biopsy were performed. Generation of multiple LV pressure-volume loops during occlusion and release of the inferior vena cava by a balloon catheter was performed using the volume signals from the echocardiographic automatated edge detection method and the pressure signals from a 5F fluid-filled lumen catheter. ESPVR was measured at the baseline and after 3 minutes of dobutamin infusion (10 μ g/Kg/min. Results:No correlation was observed between the degree of myocyte hypertrophy change or interstitial fibrosis and the two-dimensional echocardiographic or hemodynamic data. However, restrictive LV filling pattern was more common in the patients with severe degree of myocyte hypertrophy change. Myocardial |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|