MODIFIED SOLID PHASE EXTRACTION OF ORGANOPHOSPHORUS PESTICIDES; REPORT OF TWO CASES OF SUICIDES

Autor: Mohammad Zarenezhad, Reza Khoshnoud, Maryam Hosseini, Hasan Abbasinia, Saeid Gholamzadeh, Asiyeh Hashemi, Tahereh Tarian, Abdorrasoul Malekpour
Rok vydání: 2016
Předmět:
Zdroj: International Journal of Pharmacy and Biological Sciences. 6:74-77
ISSN: 2230-7605
2321-3272
DOI: 10.21276/ijpbs.2016.6.3.8
Popis: *Corresponding Author Email: saeedghmail@yahoo.com ABSTRACT Suicide is considered as the tenth cause of the death worldwide. Among different pesticides, organophosphorus pesticides (OPs) are the most widely used, but they are highly toxic, so there are increasing suicide reports about use of them. Considering the low rate of organophosphorus pesticides in the suicide reports, these two cases helped us to improve our customary methods of extraction. In this study, two cases of suicide related to a 25-yearold girl and 36-year-old man who have taken high doses of Diazinon. Both cases were dead on arrival to the hospital so no medical cases were done for them and they were brought to the Fars Legal Medicine Organization. They were suspected of using some toxins or drugs. Diazinon and Dithion were extracted using modified solid phase extraction method in the gastric content of both cases by GC-MS analysis. Modified solid phase extraction method is so helpful for toxicological analysis and detection of cause of the death in suicide, homicide or accidental died cases of organophosphorus poisoning referred to legal medicine organization.
Databáze: OpenAIRE