Leucine Aminopeptidase and Hatching of Schistosoma mansoni Eggs
Autor: | Marc H. Dresden, Yi-zheng Xu |
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Rok vydání: | 1986 |
Předmět: |
Hatching
digestive oral and skin physiology Leupeptin Biology equipment and supplies biology.organism_classification Aminopeptidase Life stage Andrology chemistry.chemical_compound chemistry parasitic diseases embryonic structures Parasitology Schistosoma mansoni Leucine human activities Leucyl aminopeptidase Ecology Evolution Behavior and Systematics |
Zdroj: | The Journal of Parasitology. 72:507 |
ISSN: | 0022-3395 |
DOI: | 10.2307/3281498 |
Popis: | Leucine aminopeptidase (LAP) activity has been measured in extracts of eggs, miracidia, cercariae and adult worms of Schistosoma mansoni. Activity measured at pH 7.2 using L-leu-7-amino-4-trifluoro-methylcoumarin as substrate is 6- to 17-fold greater in eggs than in other life stages. LAP activity is also high in soluble egg antigen preparations and in hatching fluid. The release of LAP from eggs parallels hatching, and inhibitors of LAP also inhibit hatching. The possible role of LAP in the hatching process of S. mansoni eggs is discussed. |
Databáze: | OpenAIRE |
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