Leucine Aminopeptidase and Hatching of Schistosoma mansoni Eggs

Autor: Marc H. Dresden, Yi-zheng Xu
Rok vydání: 1986
Předmět:
Zdroj: The Journal of Parasitology. 72:507
ISSN: 0022-3395
DOI: 10.2307/3281498
Popis: Leucine aminopeptidase (LAP) activity has been measured in extracts of eggs, miracidia, cercariae and adult worms of Schistosoma mansoni. Activity measured at pH 7.2 using L-leu-7-amino-4-trifluoro-methylcoumarin as substrate is 6- to 17-fold greater in eggs than in other life stages. LAP activity is also high in soluble egg antigen preparations and in hatching fluid. The release of LAP from eggs parallels hatching, and inhibitors of LAP also inhibit hatching. The possible role of LAP in the hatching process of S. mansoni eggs is discussed.
Databáze: OpenAIRE