Efficient and selective synthesis of alkoxy substituted di(pyridin-2-yl)amines and N-arylpyridin-2-ylamines

Autor:	Irina-Claudia Grig-Alexa, Christian Jarry, Iuliana Simionescu, Oana-Irina Patriciu, Jean-Michel Léger, Stéphane Massip, Adriana-Luminita Finaru, Gérald Guillaumet
Rok vydání:	2012
Předmět:	Ortho position Stannous Chloride Dihydrate Chemistry Organic Chemistry Drug Discovery Alkoxy group Nitro Biochemistry Medicinal chemistry
Zdroj:	Tetrahedron Letters. 53:1885-1888
ISSN:	0040-4039
DOI:	10.1016/j.tetlet.2012.01.084
Popis:	The formation of alkoxy substituted di(pyridin-2-yl)amines and N-arylpyridin-2-ylamines by nitro group reduction is described. Unexpected substitution of ortho with the amino at C-6 was observed during the reduction using SnCl2·2H2O in different alcohols. The influence of the nature of the atom at the 3- and 5-positions of nitro-substituted di(pyridin-2-yl)amines and N-arylpyridin-2-ylamines was investigated.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::745c4f21ed0ea2ded7854be953198f52 https://doi.org/10.1016/j.tetlet.2012.01.084 Zobrazit plný text záznamu Full Text from ScienceDirect