Large eddy simulations for blood dynamics in realistic stenotic carotids
| Autor: | L. Valdettaro, Rocco Michele Lancellotti, Alfio Quarteroni, Sanjeeb Bose, Christian Vergara |
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| Rok vydání: | 2017 |
| Předmět: |
Physics
Static model Turbulence Applied Mathematics 0206 medical engineering Isotropy Biomedical Engineering High resolution 02 engineering and technology Mechanics 030204 cardiovascular system & hematology 020601 biomedical engineering Physics::Fluid Dynamics 03 medical and health sciences Shear layer 0302 clinical medicine Classical mechanics Computational Theory and Mathematics Modeling and Simulation Vector field Molecular Biology Scale model Software Bifurcation |
| Zdroj: | International Journal for Numerical Methods in Biomedical Engineering. 33:e2868 |
| ISSN: | 2040-7939 |
| DOI: | 10.1002/cnm.2868 |
| Popis: | Summary In this paper, we consider Large Eddy Simulations (LES) for human stenotic carotids in presence of atheromasic plaque, a pathological condition where transitional effects to turbulence may occur, with relevant clinical implications such as plaque rupture. We provide a reference numerical solution obtained at high resolution without any subgrid scale model, to be used to assess the accuracy of LES simulations. In the context we are considering, i.e. hemodynamics, we cannot refer to a statistically homogeneous, isotropic and stationary turbulent regime, hence the classical Kolmogorov theory cannot be used. For this reason, a mesh size and a time step are deemed fine enough if they allow to capture all the features of the velocity field in the shear layers developed after the bifurcation. To assess these requirements, we consider a simplified model of the evolution of a 2D shear layer, a relevant process in the formation of transitional effects in our case. Then, we compare the results of LES σ model (both static and dynamic) and of mixed LES models (where also a similarity contribution is considered). In particular, we consider a realistic scenario of a human carotid and we use the reference solution as gold standard. The results highlight the accuracy of the LES σ models, especially for the static model. This article is protected by copyright. All rights reserved. |
| Databáze: | OpenAIRE |
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