Preparation of carbocyclic phosphonate nucleosides
Autor: | Gerhard Jähne, Otto Holzhäuser, Irvin Winkler, Günther Rieß, Herbert Kroha, Matthias Helsberg, Manfred Rösner, Armin Müller, Christoph Dr Meichsner |
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Rok vydání: | 1992 |
Předmět: | |
Zdroj: | Tetrahedron Letters. 33:5335-5338 |
ISSN: | 0040-4039 |
Popis: | A versatile and high-yielding synthesis of racemic carbocyclic phosphonate nucleosides of adenine, hypoxanthine, guanine, cytosine, uracil, and thymine has been developed. These newly prepared compounds are isosteric (and isoelectronic) with (carbo)cyclic 2′,3′-dideoxy- and 2′,3′-dideoxy-2′,3′-didehydronucleoside monophosphates. |
Databáze: | OpenAIRE |
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